CATH Domain 2lf8A01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	transcription factor ETV6 isoform X2

Enzyme Information

UniProtKB Entries (1)

ETV6_MOUSE

Mus musculus

Transcription factor ETV6

PDB Structure

PDB	2LF8
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain. Coyne, H.J., De, S., Okon, M., Green, S.M., Bhachech, N., Graves, B.J., McIntosh, L.P. J.Mol.Biol.