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CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Transcription initiation factor TFIIH subunit

Enzyme Information

UniProtKB Entries (2)

P04486
VP16_HHV1F
Human alphaherpesvirus 1 strain F
Tegument protein VP16
P32776
TFB1_YEAST
Saccharomyces cerevisiae S288C
General transcription and DNA repair factor IIH subunit TFB1

PDB Structure

PDB 2K2U
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53.
Langlois, C., Mas, C., Di Lello, P., Jenkins, L.M., Legault, P., Omichinski, J.G.
J.Am.Chem.Soc.
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