CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

P02829
HSP82_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent molecular chaperone HSP82

PDB Structure

PDB 2IWS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of Hsp90 with Synthetic Macrolactones: Synthesis and Structural and Biological Evaluation of Ring and Conformational Analogs of Radicicol.
Proisy, N., Sharp, S.Y., Boxall, K., Connelly, S., Roe, S.M., Prodromou, C., Slawin, A.M.Z., Pearl, L.H., Workman, P., Moody, C.J.
Chem.Biol.