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CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family Aspartate aminotransferase

Enzyme Information

2.6.1.3
Cysteine transaminase.
based on mapping to UniProt P00504
L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
2.6.1.1
Aspartate transaminase.
based on mapping to UniProt P00504
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

P00504
AATC_CHICK
Gallus gallus
Aspartate aminotransferase, cytoplasmic

PDB Structure

PDB 2CST
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the closed form of chicken cytosolic aspartate aminotransferase at 1.9 A resolution.
Malashkevich, V.N., Strokopytov, B.V., Borisov, V.V., Dauter, Z., Wilson, K.S., Torchinsky, Y.M.
J.Mol.Biol.
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