CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1280 | Alpha/beta knot |
|
3.40.1280.10 | SPOUT methyltransferase, trefoil knot domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.1280.10 |
| Functional Family | tRNA (guanosine(18)-2'-O)-methyltransferase |
Enzyme Information
| 2.1.1.34 |
tRNA (guanosine(18)-2'-O)-methyltransferase.
based on mapping to UniProt Q5SM16
S-adenosyl-L-methionine + guanosine(18) in tRNA = S-adenosyl-L- homocysteine + 2'-O-methylguanosine(18) in tRNA.
-!- The enzyme catalyzes the methylation of guanosine(18) in tRNA.
|
UniProtKB Entries (1)
| Q5SM16 |
TRMH_THET8
Thermus thermophilus HB8
TRNA (guanosine(18)-2'-O)-methyltransferase
|
PDB Structure
| PDB | 1V2X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Spodoptera |
| Primary Citation |
Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
STRUCTURE
|