CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family SHC-transforming protein 1 isoform 3

Enzyme Information

UniProtKB Entries (1)

P04629
NTRK1_HUMAN
Homo sapiens
High affinity nerve growth factor receptor

PDB Structure

PDB 1SHC
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Zhou, M.M., Ravichandran, K.S., Olejniczak, E.F., Petros, A.M., Meadows, R.P., Sattler, M., Harlan, J.E., Wade, W.S., Burakoff, S.J., Fesik, S.W.
Nature