CATH Classification

Domain Context

CATH Clusters

Superfamily Rhodanese-like domain
Functional Family M-phase inducer phosphatase 2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P30305
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P30305
MPIP2_HUMAN
Homo sapiens
M-phase inducer phosphatase 2

PDB Structure

PDB 1QB0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
Reynolds, R.A., Yem, A.W., Wolfe, C.L., Deibel Jr., M.R., Chidester, C.G., Watenpaugh, K.D.
J.Mol.Biol.