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1 keywords

CATH Domain 1mduD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.20 Severin
Homologous Superfamily 3.40.20.10 Severin

Domain Context

CATH Clusters

Superfamily Severin
Functional Family Gelsolin

Enzyme Information

UniProtKB Entries (2)

P06396
GELS_HUMAN
Homo sapiens
Gelsolin
P68139
ACTS_CHICK
Gallus gallus
Actin, alpha skeletal muscle

PDB Structure

PDB 1MDU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing
Dawson, J.F., Sablin, E.P., Spudich, J.A., Fletterick, R.J.
J.Biol.Chem.
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