CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

4.1.1.64
2,2-dialkylglycine decarboxylase (pyruvate).
based on mapping to UniProt P16932
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO(2) + L-alanine.
-!- Acts on 2-amino-2-methylpropanoate (i.e. 2-methylalanine), 2-amino-2- methylbutanoate and 1-aminocyclopentanecarboxylate.

UniProtKB Entries (1)

P16932
DGDA_BURCE
Burkholderia cepacia
2,2-dialkylglycine decarboxylase

PDB Structure

PDB 1M0N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Aminophosphonate Inhibitors of Dialkylglycine Decarboxylase: Structural Basis for Slow Binding Inhibition
Liu, W., Rogers, C.J., Fisher, A.J., Toney, M.D.
Biochemistry