CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Transcriptional regulator URE2

Enzyme Information

1.8.4.-
With a disulfide as acceptor.
based on mapping to UniProt P23202
1.11.1.9
Glutathione peroxidase.
based on mapping to UniProt P23202
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).

UniProtKB Entries (1)

P23202
URE2_YEAST
Saccharomyces cerevisiae S288C
Transcriptional regulator URE2

PDB Structure

PDB 1JZR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
Bousset, L., Belrhali, H., Melki, R., Morera, S.
Biochemistry