CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family

Enzyme Information

3.1.22.4
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt Q7LXU0
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.

UniProtKB Entries (1)

Q7LXU0
HJC_SACS2
Saccharolobus solfataricus P2
Holliday junction resolvase Hjc

PDB Structure

PDB 1HH1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Hjc, a Holliday Junction Resolvase, from Sulfolobus Solfataricus
Bond, C.S., Kvaratskhelia, M., Richard, D., White, M.F., Hunter, W.N.
Proc.Natl.Acad.Sci.USA