CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.200 | Tumour Suppressor Smad4 |
|
2.60.200.20 |
Domain Context
CATH Clusters
| Superfamily | 2.60.200.20 |
| Functional Family |
Enzyme Information
| 2.7.12.1 |
Dual-specificity kinase.
based on mapping to UniProt P22216
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.
|
UniProtKB Entries (1)
| P22216 |
RAD53_YEAST
Saccharomyces cerevisiae S288C
Serine/threonine-protein kinase RAD53
|
PDB Structure
| PDB | 1G6G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
Mol.Cell
|
