CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Glutathione S-transferase A1

Enzyme Information

1.11.1.-
Peroxidases.
based on mapping to UniProt P13745
2.5.1.18
Glutathione transferase.
based on mapping to UniProt P13745
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
5.3.3.-
Transposing C=C bonds.
based on mapping to UniProt P13745

UniProtKB Entries (1)

P13745
GSTA1_MOUSE
Mus musculus
Glutathione S-transferase A1

PDB Structure

PDB 1F3A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide.
Gu, Y., Singh, S.V., Ji, X.
Biochemistry