CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P14420
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P04084
PA2A_VIPAE
Vipera ammodytes meridionalis
Acidic phospholipase A2 homolog vipoxin A chain

PDB Structure

PDB 1AOK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolution.
Perbandt, M., Wilson, J.C., Eschenburg, S., Mancheva, I., Aleksiev, B., Genov, N., Willingmann, P., Weber, W., Singh, T.P., Betzel, C.
FEBS Lett.