The name of this superfamily has been modified since the most recent official CATH+ release (current). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 561: rho-related GTP-binding protein RhoV

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 Q7L0Q8 (/IPI) Q7L0Q8 (/IPI) Q7L0Q8 (/IPI) Q7L0Q8 (/IPI) Q96L33 (/IPI) Q96L33 (/IPI) Q96L33 (/IPI) Q96L33 (/IPI) Q96L33 (/IPI) Q96L33 (/IPI)
(1 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q9EQT3 (/IMP)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of small GTPase mediated signal transduction GO:0051056
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
10 Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
4 Q7L0Q8 (/IMP) Q7L0Q8 (/IMP) Q7L0Q8 (/IMP) Q7L0Q8 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 Q7L0Q8 (/IMP) Q7L0Q8 (/IMP) Q7L0Q8 (/IMP) Q7L0Q8 (/IMP)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
4 Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS)
Positive regulation of protein targeting to mitochondrion GO:1903955
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
4 Q7L0Q8 (/HMP) Q7L0Q8 (/HMP) Q7L0Q8 (/HMP) Q7L0Q8 (/HMP)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
2 A5D7J5 (/ISS) Q9EQT3 (/ISS)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
2 Q52WY4 (/IMP) Q5U3T8 (/IMP)
Atrioventricular canal development GO:0036302
The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.
2 Q52WY4 (/IMP) Q5U3T8 (/IMP)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
1 Q9EQT3 (/IDA)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 Q9EQT3 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q9Z1Y0 (/IDA)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q8VDU1 (/ISO)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q9EQT3 (/IDA)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q9EQT3 (/ISO)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 A5D7J5 (/ISS)
Rac protein signal transduction GO:0016601
A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
1 Q9EQT3 (/IDA)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q9EQT3 (/IDA)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
1 Q5YLG6 (/IMP)
Protein localization to adherens junction GO:0071896
Any process in which a protein is transported to, and/or maintained at the adherens junction.
1 Q5YLG6 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q7L0Q8 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS) Q96L33 (/TAS)
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