The name of this superfamily has been modified since the most recent official CATH+ release (current). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2482: Large-subunit GTPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 P53145 (/HDA) P53145 (/HDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 P53145 (/ISS) P53145 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P53145 (/IPI) P53145 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
2 P53145 (/IMP) P53145 (/IMP)
Ribosomal subunit export from nucleus GO:0000054
The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
2 P53145 (/IMP) P53145 (/IMP)
Conjugation with cellular fusion GO:0000747
A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.
2 P53145 (/IMP) P53145 (/IMP)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
2 P53145 (/IMP) P53145 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P53145 (/IDA) P53145 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P53145 (/HDA) P53145 (/HDA)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
2 P53145 (/IDA) P53145 (/IDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
2 P53145 (/HDA) P53145 (/HDA)
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