The name of this superfamily has been modified since the most recent official CATH+ release (current). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2140: Small GTP-binding protein Rab11

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
8 D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
8 D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
8 D6XLG8 (/IMP) D6XLG8 (/IMP) D6XLG8 (/IMP) D6XLG8 (/IMP) Q9NJE8 (/IMP) Q9NJE8 (/IMP) Q9NJE8 (/IMP) Q9NJE8 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
8 D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) D6XLG8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM) Q9NJE8 (/ISM)
Endosomal transport GO:0016197
The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
8 D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Contractile vacuole GO:0000331
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory.
9 D6XLG8 (/ISO) D6XLG8 (/ISO) D6XLG8 (/ISO) D6XLG8 (/ISO) Q4QHC3 (/ISO) Q9NJE8 (/ISO) Q9NJE8 (/ISO) Q9NJE8 (/ISO) Q9NJE8 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
8 D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
8 D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) D6XLG8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA) Q9NJE8 (/IDA)
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