The name of this superfamily has been modified since the most recent official CATH+ release (current). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1027: dynamin-related protein 3A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
10 F4JJ15 (/IDA) F4JJ15 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
10 P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) P54861 (/IPI) Q8S944 (/IPI) Q8S944 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q8S944 (/IPI) Q8S944 (/IPI)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
2 F4JJ15 (/IDA) F4JJ15 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 L5LMA2 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 L5LMA2 (/ISS)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion inheritance GO:0000001
The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.
8 P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
8 P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
8 P54861 (/TAS) P54861 (/TAS) P54861 (/TAS) P54861 (/TAS) P54861 (/TAS) P54861 (/TAS) P54861 (/TAS) P54861 (/TAS)
Chronological cell aging GO:0001300
The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
8 P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Vesicle organization GO:0016050
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
8 P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP) P54861 (/IMP)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
8 P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI) P54861 (/IGI)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
2 F4JJ15 (/IMP) F4JJ15 (/IMP)
Regulation of peroxisome size GO:0044375
Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
2 F4JJ15 (/IGI) F4JJ15 (/IGI)
Necroptotic process GO:0070266
A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.
1 L5LMA2 (/ISS)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
12 F4JJ15 (/IDA) F4JJ15 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
(2 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 F4JJ15 (/IDA) F4JJ15 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 F4JJ15 (/IDA) F4JJ15 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 P54861 (/HDA) P54861 (/HDA) P54861 (/HDA) P54861 (/HDA) P54861 (/HDA) P54861 (/HDA) P54861 (/HDA) P54861 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
8 P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA) P54861 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 F4JJ15 (/IDA) F4JJ15 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 F4JJ15 (/IDA) F4JJ15 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 F4JJ15 (/IDA) F4JJ15 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 L5LMA2 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 L5LMA2 (/ISS)
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