The name of this superfamily has been modified since the most recent official CATH+ release (current). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 2714: CD45
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of T cell mediated cytotoxicity GO:0001915
Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Negative regulation of cytokine-mediated signaling pathway GO:0001960
Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Positive regulation of antigen receptor-mediated signaling pathway GO:0050857
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Release of sequestered calcium ion into cytosol GO:0051209
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
3 | Q6ED60 (/ISS) Q6ED61 (/ISS) Q6ED62 (/ISS) |
