PDB Information

PDB6GIN
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept.
Hudson, L., Mui, J., Vazquez, S., Carvalho, D.M., Williams, E., Jones, C., Bullock, A.N., Hoelder, S.
J. Med. Chem.
HeaderSignaling Protein
Released2018-05-14
Resolution2.200
CATH Insert Date03 Jun, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6ginA01 29 Jun, 2018 3.30.200.20 Assigned
6ginA02 29 Jun, 2018 1.10.510.10 Assigned
6ginB01 29 Jun, 2018 3.30.200.20 Assigned
6ginB02 29 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q04771 ACVR1_HUMAN Homo sapiens Activin receptor type-1
Q04771 ACVR1_HUMAN Homo sapiens Activin receptor type-1