PDB Information

Host OrganismSpodoptera aff. frugiperda 2 RZ-2014
Gene SourceHomo sapiens
Primary Citation
Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.
Waldschmidt, H.V., Bouley, R., Kirchhoff, P.D., Lee, P., Tesmer, J.J.G., Larsen, S.D.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Signaling Protein
CATH Insert Date03 Jun, 2018

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
G 03 Jun, 2018 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
6c2yA01 28 Jun, 2018 Assigned
6c2yA02 28 Jun, 2018 Assigned
6c2yA03 28 Jun, 2018 Assigned
6c2yA04 28 Jun, 2018 1.10.510.10 Assigned
6c2yA05 28 Jun, 2018 Assigned
6c2yB00 28 Jun, 2018 Assigned
6c2yG00 28 Jun, 2018 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P63212 GBG2_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P62871 GBB1_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
P25098 ARBK1_HUMAN Homo sapiens Beta-adrenergic receptor kinase 1