PDB Information

PDB5WG4
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia
Gene SourceHomo sapiens
Primary Citation
Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Bouley, R., Waldschmidt, H.V., Cato, M.C., Cannavo, A., Song, J., Cheung, J.Y., Yao, X.Q., Koch, W.J., Larsen, S.D., Tesmer, J.J.G.
Mol. Pharmacol.
HeaderTransferase/Signaling Protein
Released2017-07-13
Resolution2.310
CATH Insert Date07 Jan, 2018

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
G 07 Jan, 2018 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
5wg4A01 11 Jan, 2018 1.10.287.1270 Assigned
5wg4A02 11 Jan, 2018 1.10.167.10 Assigned
5wg4A03 11 Jan, 2018 3.30.200.20 Assigned
5wg4A04 11 Jan, 2018 1.10.510.10 Assigned
5wg4A05 11 Jan, 2018 2.30.29.30 Assigned
5wg4B00 11 Jan, 2018 2.130.10.10 Assigned
5wg4G00 11 Jan, 2018 4.10.260.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P25098 ARBK1_HUMAN Homo sapiens Beta-adrenergic receptor kinase 1
P62871 GBB1_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
P63212 GBG2_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2