PDB Information

PDB5HJS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification and in Vivo Evaluation of Liver X Receptor beta-Selective Agonists for the Potential Treatment of Alzheimer's Disease.
Stachel, S.J., Zerbinatti, C., Rudd, M.T., Cosden, M., Suon, S., Nanda, K.K., Wessner, K., DiMuzio, J., Maxwell, J., Wu, Z., Uslaner, J.M., Michener, M.S., Szczerba, P., Brnardic, E., Rada, V., Kim, Y., Meissner, R., Wuelfing, P., Yuan, Y., Ballard, J., Holahan, M., Klein, D.J., Lu, J., Fradera, X., Parthasarathy, G., Uebele, V.N., Chen, Z., Li, Y., Li, J., Cooke, A.J., Bennett, D.J., Bilodeau, M.T., Renger, J.
J.Med.Chem.
HeaderSignaling Protein
Released2016-01-13
Resolution1.720
CATH Insert Date17 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Rejected
D 18 Apr, 2016 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5hjsA00 30 Nov, 2016 1.10.565.10 Assigned
5hjsB00 30 Nov, 2016 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
Q13133 NR1H3_HUMAN Homo sapiens Oxysterols receptor LXR-alpha
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
Q13133 NR1H3_HUMAN Homo sapiens Oxysterols receptor LXR-alpha