CATH Domain 5hjsB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

NCOA1_HUMAN

Homo sapiens

Nuclear receptor coactivator 1

PDB Structure

PDB	5HJS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and in Vivo Evaluation of Liver X Receptor beta-Selective Agonists for the Potential Treatment of Alzheimer's Disease. Stachel, S.J., Zerbinatti, C., Rudd, M.T., Cosden, M., Suon, S., Nanda, K.K., Wessner, K., DiMuzio, J., Maxwell, J., Wu, Z., Uslaner, J.M., Michener, M.S., Szczerba, P., Brnardic, E., Rada, V., Kim, Y., Meissner, R., Wuelfing, P., Yuan, Y., Ballard, J., Holahan, M., Klein, D.J., Lu, J., Fradera, X., Parthasarathy, G., Uebele, V.N., Chen, Z., Li, Y., Li, J., Cooke, A.J., Bennett, D.J., Bilodeau, M.T., Renger, J. J.Med.Chem.