PDB Information

PDB5HE2
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceBos taurus
Primary Citation
Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
Waldschmidt, H.V., Homan, K.T., Cruz-Rodriguez, O., Cato, M.C., Waninger-Saroni, J., Larimore, K.M., Cannavo, A., Song, J., Cheung, J.Y., Kirchhoff, P.D., Koch, W.J., Tesmer, J.J., Larsen, S.D.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-01-05
Resolution2.790
CATH Insert Date29 May, 2016

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped
G 30 May, 2016 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
5he2A01 28 Feb, 2017 1.10.287.1270 Assigned
5he2A02 28 Feb, 2017 1.10.167.10 Assigned
5he2A03 28 Feb, 2017 3.30.200.20 Assigned
5he2A04 28 Feb, 2017 1.10.510.10 Assigned
5he2A05 28 Feb, 2017 2.30.29.30 Assigned
5he2B00 16 Jul, 2016 2.130.10.10 Assigned
5he2G00 16 Jul, 2016 4.10.260.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P62873 GBB1_HUMAN Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
P59768 GBG2_HUMAN Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P21146 ARBK1_BOVIN Bos taurus Beta-adrenergic receptor kinase 1