PDB 5apk

PDB Links
Overview

PDB Information

PDB	5APK
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma. Olsson, R.I., Xue, Y., von Berg, S., Aagaard, A., McPheat, J., Hansson, E.L., Bernstrom, J., Hansson, P., Jirholt, J., Grindebacke, H., Leffler, A., Chen, R., Xiong, Y., Ge, H., Hansson, T.G., Narjes, F. ChemMedChem
Header	Transcription
Released	2015-09-16
Resolution	2.100
CATH Insert Date	06 Dec, 2015

PDB Images (6)

Image of CATH 5apk

5apk

PDB 5apk

Image of CATH 5apkA

5apkA

PDB Chain 5apkA

Image of CATH 5apkB

5apkB

PDB Chain 5apkB

Image of CATH 5apkD

5apkD

PDB Chain 5apkD

Image of CATH 5apkA00

5apkA00

CATH Domain 5apkA00

Image of CATH 5apkB00

5apkB00

CATH Domain 5apkB00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	07 Dec, 2015	Chopped
B	07 Dec, 2015	Chopped
D	07 Dec, 2015	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5apkA00	05 Jan, 2016	1.10.565.10	Assigned
5apkB00	05 Jan, 2016	1.10.565.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P51449	RORG_HUMAN	Homo sapiens	Nuclear receptor ROR-gamma
P51449	RORG_HUMAN	Homo sapiens	Nuclear receptor ROR-gamma
P51449	RORG_HUMAN	Homo sapiens	Nuclear receptor ROR-gamma