CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

P51449
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma

PDB Structure

PDB 5APK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma.
Olsson, R.I., Xue, Y., von Berg, S., Aagaard, A., McPheat, J., Hansson, E.L., Bernstrom, J., Hansson, P., Jirholt, J., Grindebacke, H., Leffler, A., Chen, R., Xiong, Y., Ge, H., Hansson, T.G., Narjes, F.
ChemMedChem