PDB 4qm0

PDB Information

PDB4QM0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.
Fauber, B.P., Rene, O., de Leon Boenig, G., Burton, B., Deng, Y., Eidenschenk, C., Everett, C., Gobbi, A., Hymowitz, S.G., Johnson, A.R., La, H., Liimatta, M., Lockey, P., Norman, M., Ouyang, W., Wang, W., Wong, H.
Bioorg.Med.Chem.Lett.
HeaderTranscription/Transcription Inhibitor
Released2014-06-14
Resolution2.200
CATH Insert Date28 Sep, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Sep, 2014 Chopped
C 29 Sep, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4qm0A00 07 Oct, 2014 1.10.565.10 Assigned
4qm0C00 08 Oct, 2014 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma