CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

P51449
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma

PDB Structure

PDB 4QM0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.
Fauber, B.P., Rene, O., de Leon Boenig, G., Burton, B., Deng, Y., Eidenschenk, C., Everett, C., Gobbi, A., Hymowitz, S.G., Johnson, A.R., La, H., Liimatta, M., Lockey, P., Norman, M., Ouyang, W., Wang, W., Wong, H.
Bioorg.Med.Chem.Lett.