PDB 4i0p

PDB Information

PDB4I0P
MethodX-RAY DIFFRACTION
Host OrganismDrosophila melanogaster
Gene SourceHomo sapiens
Primary Citation
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.
Guce, A.I., Mortimer, S.E., Yoon, T., Painter, C.A., Jiang, W., Mellins, E.D., Stern, L.J.
Nat.Struct.Mol.Biol.
HeaderImmune System
Released2012-11-18
Resolution3.200
CATH Insert Date30 Dec, 2012

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped
B 31 Dec, 2012 Chopped
C 31 Dec, 2012 Chopped
D 31 Dec, 2012 Chopped
E 31 Dec, 2012 Chopped
F 31 Dec, 2012 Chopped
G 31 Dec, 2012 Chopped
H 31 Dec, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4i0pA01 02 Jan, 2013 3.10.320.10 Assigned
4i0pA02 02 Jan, 2013 2.60.40.10 Assigned
4i0pB01 02 Jan, 2013 3.10.320.10 Assigned
4i0pB02 02 Jan, 2013 2.60.40.10 Assigned
4i0pC01 03 Jan, 2013 3.10.320.10 Assigned
4i0pC02 03 Jan, 2013 2.60.40.10 Assigned
4i0pD01 03 Jan, 2013 3.10.320.10 Assigned
4i0pD02 03 Jan, 2013 2.60.40.10 Assigned
4i0pE01 02 Jan, 2013 3.10.320.10 Assigned
4i0pE02 02 Jan, 2013 2.60.40.10 Assigned
4i0pF01 02 Jan, 2013 3.10.320.10 Assigned
4i0pF02 02 Jan, 2013 2.60.40.10 Assigned
4i0pG01 03 Jan, 2013 3.10.320.10 Assigned
4i0pG02 03 Jan, 2013 2.60.40.10 Assigned
4i0pH01 03 Jan, 2013 3.10.320.10 Assigned
4i0pH02 03 Jan, 2013 2.60.40.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q6ICR9 Q6ICR9_HUMAN Homo sapiens HLA-DMA protein
P13765 DOB_HUMAN Homo sapiens HLA class II histocompatibility antigen, DO beta chain
Q6ICR9 Q6ICR9_HUMAN Homo sapiens HLA-DMA protein
P28068 DMB_HUMAN Homo sapiens HLA class II histocompatibility antigen, DM beta chain
P28068 DMB_HUMAN Homo sapiens HLA class II histocompatibility antigen, DM beta chain
P06340 DOA_HUMAN Homo sapiens HLA class II histocompatibility antigen, DO alpha chain
P06340 DOA_HUMAN Homo sapiens HLA class II histocompatibility antigen, DO alpha chain
P13765 DOB_HUMAN Homo sapiens HLA class II histocompatibility antigen, DO beta chain