CATH Domain 4i0pB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.320	Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1
	3.10.320.10	Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1

Domain Context

CATH Clusters

Superfamily	Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1
Functional Family	MHC class II H2-M beta 2 chain

Enzyme Information

UniProtKB Entries (1)

DOA_HUMAN

Homo sapiens

HLA class II histocompatibility antigen, DO alpha chain

PDB Structure

PDB	4I0P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Guce, A.I., Mortimer, S.E., Yoon, T., Painter, C.A., Jiang, W., Mellins, E.D., Stern, L.J. Nat.Struct.Mol.Biol.