PDB 4gm8

PDB Links
Overview

PDB Information

PDB	4GM8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. Karatas, H., Townsend, E.C., Cao, F., Chen, Y., Bernard, D., Liu, L., Lei, M., Dou, Y., Wang, S. J.Am.Chem.Soc.
Header	Transcription/Transcription Inhibitor
Released	2012-08-15
Resolution	2.600
CATH Insert Date	18 Aug, 2013

PDB Images (13)

Image of CATH 4gm8

4gm8

PDB 4gm8

Image of CATH 4gm8A

4gm8A

PDB Chain 4gm8A

Image of CATH 4gm8B

4gm8B

PDB Chain 4gm8B

Image of CATH 4gm8C

4gm8C

PDB Chain 4gm8C

Image of CATH 4gm8D

4gm8D

PDB Chain 4gm8D

Image of CATH 4gm8E

4gm8E

PDB Chain 4gm8E

Image of CATH 4gm8F

4gm8F

PDB Chain 4gm8F

Image of CATH 4gm8G

4gm8G

PDB Chain 4gm8G

Image of CATH 4gm8H

4gm8H

PDB Chain 4gm8H

Image of CATH 4gm8A00

4gm8A00

CATH Domain 4gm8A00

Image of CATH 4gm8B00

4gm8B00

CATH Domain 4gm8B00

Image of CATH 4gm8C00

4gm8C00

CATH Domain 4gm8C00

Image of CATH 4gm8D00

4gm8D00

CATH Domain 4gm8D00

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	19 Aug, 2013	Chopped
B	19 Aug, 2013	Chopped
C	19 Aug, 2013	Chopped
D	19 Aug, 2013	Chopped
E	19 Aug, 2013	Rejected
F	19 Aug, 2013	Rejected
G	19 Aug, 2013	Rejected
H	19 Aug, 2013	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gm8A00	27 Aug, 2013	2.130.10.10	Assigned
4gm8B00	27 Aug, 2013	2.130.10.10	Assigned
4gm8C00	27 Aug, 2013	2.130.10.10	Assigned
4gm8D00	23 Aug, 2013	2.130.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P61964	WDR5_HUMAN	Homo sapiens	WD repeat-containing protein 5
P61964	WDR5_HUMAN	Homo sapiens	WD repeat-containing protein 5
P61964	WDR5_HUMAN	Homo sapiens	WD repeat-containing protein 5
P61964	WDR5_HUMAN	Homo sapiens	WD repeat-containing protein 5