PDB 4gm8

PDB Information

PDB4GM8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
Karatas, H., Townsend, E.C., Cao, F., Chen, Y., Bernard, D., Liu, L., Lei, M., Dou, Y., Wang, S.
J.Am.Chem.Soc.
HeaderTranscription/Transcription Inhibitor
Released2012-08-15
Resolution2.600
CATH Insert Date18 Aug, 2013

PDB Images (13)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2013 Chopped
B 19 Aug, 2013 Chopped
C 19 Aug, 2013 Chopped
D 19 Aug, 2013 Chopped
E 19 Aug, 2013 Rejected
F 19 Aug, 2013 Rejected
G 19 Aug, 2013 Rejected
H 19 Aug, 2013 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4gm8A00 27 Aug, 2013 2.130.10.10 Assigned
4gm8B00 27 Aug, 2013 2.130.10.10 Assigned
4gm8C00 27 Aug, 2013 2.130.10.10 Assigned
4gm8D00 23 Aug, 2013 2.130.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5