CATH Domain 4gm8C00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	WD repeat-containing protein 5

Enzyme Information

UniProtKB Entries (1)

WDR5_HUMAN

Homo sapiens

WD repeat-containing protein 5

PDB Structure

PDB	4GM8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. Karatas, H., Townsend, E.C., Cao, F., Chen, Y., Bernard, D., Liu, L., Lei, M., Dou, Y., Wang, S. J.Am.Chem.Soc.