PDB 3zrf

PDB Information

PDB3ZRF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction
Buckley, D.L., Van Molle, I., Gareiss, P.C., Tae, H.S., Michel, J., Noblin, D.J., Jorgensen, W.L., Ciulli, A., Crews, C.M.
J.Am.Chem.Soc.
HeaderTranscription
Released2011-06-16
Resolution2.800
CATH Insert Date27 May, 2012

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
E 28 May, 2012 Chopped
F 28 May, 2012 Chopped
G 28 May, 2012 Chopped
H 28 May, 2012 Chopped
I 28 May, 2012 Chopped
J 28 May, 2012 Chopped
K 28 May, 2012 Chopped
L 28 May, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3zrfA00 08 Jun, 2012 3.10.20.90 Assigned
3zrfB00 08 Jun, 2012 3.30.710.10 Assigned
3zrfC01 08 Jun, 2012 2.60.40.780 Assigned
3zrfC02 08 Jun, 2012 1.10.750.10 Assigned
3zrfD00 08 Jun, 2012 3.10.20.90 Assigned
3zrfE00 08 Jun, 2012 3.30.710.10 Assigned
3zrfF01 08 Jun, 2012 2.60.40.780 Assigned
3zrfF02 08 Jun, 2012 1.10.750.10 Assigned
3zrfG00 08 Jun, 2012 3.10.20.90 Assigned
3zrfH00 08 Jun, 2012 3.30.710.10 Assigned
3zrfI01 08 Jun, 2012 2.60.40.780 Assigned
3zrfI02 08 Jun, 2012 1.10.750.10 Assigned
3zrfJ00 08 Jun, 2012 3.10.20.90 Assigned
3zrfK00 08 Jun, 2012 3.30.710.10 Assigned
3zrfL01 08 Jun, 2012 2.60.40.780 Assigned
3zrfL02 08 Jun, 2012 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor