PDB 3kn2

PDB Links
Overview

PDB Information

PDB	3KN2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus subtype 1a
Primary Citation	P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Nair, L.G., Sannigrahi, M., Bogen, S., Pinto, P., Chen, K.X., Prongay, A., Tong, X., Cheng, K.C., Girijavallabhan, V., George Njoroge, F. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2009-11-11
Resolution	2.300
CATH Insert Date	21 Jan, 2010

PDB Images (9)

Image of CATH 3kn2

3kn2

PDB 3kn2

Image of CATH 3kn2A

3kn2A

PDB Chain 3kn2A

Image of CATH 3kn2B

3kn2B

PDB Chain 3kn2B

Image of CATH 3kn2C

3kn2C

PDB Chain 3kn2C

Image of CATH 3kn2D

3kn2D

PDB Chain 3kn2D

Image of CATH 3kn2A01

3kn2A01

CATH Domain 3kn2A01

Image of CATH 3kn2A02

3kn2A02

CATH Domain 3kn2A02

Image of CATH 3kn2C01

3kn2C01

CATH Domain 3kn2C01

Image of CATH 3kn2C02

3kn2C02

CATH Domain 3kn2C02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	22 Jan, 2010	Chopped
B	22 Jan, 2010	Rejected
C	22 Jan, 2010	Chopped
D	22 Jan, 2010	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3kn2A01	23 Jun, 2010	2.40.10.120	Assigned
3kn2A02	23 Jun, 2010	2.40.10.10	Assigned
3kn2C01	23 Jun, 2010	2.40.10.120	Assigned
3kn2C02	23 Jun, 2010	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P26664	POLG_HCV1	Hepatitis C virus (isolate 1)	Genome polyprotein
Q9WMX2	POLG_HCVCO	Hepatitis C virus (isolate Con1)	Genome polyprotein
P26664	POLG_HCV1	Hepatitis C virus (isolate 1)	Genome polyprotein
Q9WMX2	POLG_HCVCO	Hepatitis C virus (isolate Con1)	Genome polyprotein