PDB 3hbb

PDB Information

PDB3HBB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceTrypanosoma cruzi
Primary Citation
Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
Senkovich, O., Schormann, N., Chattopadhyay, D.
Acta Crystallogr.,Sect.D
HeaderOxidoreductase, Transferase
Released2009-05-04
Resolution3.000
CATH Insert Date16 Aug, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3hbbA01 11 May, 2013 3.40.430.10 Assigned
3hbbA02 11 May, 2013 3.30.572.10 Assigned
3hbbB01 11 May, 2013 3.40.430.10 Assigned
3hbbB02 11 May, 2013 3.30.572.10 Assigned
3hbbC01 11 May, 2013 3.40.430.10 Assigned
3hbbC02 11 May, 2013 3.30.572.10 Assigned
3hbbD01 11 May, 2013 3.40.430.10 Assigned
3hbbD02 11 May, 2013 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase