PDB 3e4a

PDB Links
Overview

PDB Information

PDB	3E4A
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. Leissring, M.A., Malito, E., Hedouin, S., Reinstatler, L., Sahara, T., Abdul-Hay, S.O., Choudhry, S., Maharvi, G.M., Fauq, A.H., Huzarska, M., May, P.S., Choi, S., Logan, T.P., Turk, B.E., Cantley, L.C., Manolopoulou, M., Tang, W.J., Stein, R.L., Cuny, G.D., Selkoe, D.J. Plos One
Header	Hydrolase
Released	2008-08-11
Resolution	2.600
CATH Insert Date	16 Aug, 2009

PDB Images (13)

Image of CATH 3e4a

3e4a

PDB 3e4a

Image of CATH 3e4aA

3e4aA

PDB Chain 3e4aA

Image of CATH 3e4aB

3e4aB

PDB Chain 3e4aB

Image of CATH 3e4aF

3e4aF

PDB Chain 3e4aF

Image of CATH 3e4aG

3e4aG

PDB Chain 3e4aG

Image of CATH 3e4aA01

3e4aA01

CATH Domain 3e4aA01

Image of CATH 3e4aA02

3e4aA02

CATH Domain 3e4aA02

Image of CATH 3e4aA03

3e4aA03

CATH Domain 3e4aA03

Image of CATH 3e4aA04

3e4aA04

CATH Domain 3e4aA04

Image of CATH 3e4aB01

3e4aB01

CATH Domain 3e4aB01

Image of CATH 3e4aB02

3e4aB02

CATH Domain 3e4aB02

Image of CATH 3e4aB03

3e4aB03

CATH Domain 3e4aB03

Image of CATH 3e4aB04

3e4aB04

CATH Domain 3e4aB04

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped
B	16 Aug, 2009	Chopped
F	16 Aug, 2009	Rejected
G	16 Aug, 2009	Rejected

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3e4aA01	30 Aug, 2013	3.30.830.10	Assigned
3e4aA02	30 Aug, 2013	3.30.830.10	Assigned
3e4aA03	30 Aug, 2013	3.30.830.10	Assigned
3e4aA04	30 Aug, 2013	3.30.830.10	Assigned
3e4aB01	30 Aug, 2013	3.30.830.10	Assigned
3e4aB02	30 Aug, 2013	3.30.830.10	Assigned
3e4aB03	30 Aug, 2013	3.30.830.10	Assigned
3e4aB04	30 Aug, 2013	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme