PDB 3e4a

PDB Information

PDB3E4A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Leissring, M.A., Malito, E., Hedouin, S., Reinstatler, L., Sahara, T., Abdul-Hay, S.O., Choudhry, S., Maharvi, G.M., Fauq, A.H., Huzarska, M., May, P.S., Choi, S., Logan, T.P., Turk, B.E., Cantley, L.C., Manolopoulou, M., Tang, W.J., Stein, R.L., Cuny, G.D., Selkoe, D.J.
Plos One
HeaderHydrolase
Released2008-08-11
Resolution2.600
CATH Insert Date16 Aug, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
F 16 Aug, 2009 Rejected
G 16 Aug, 2009 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3e4aA01 30 Aug, 2013 3.30.830.10 Assigned
3e4aA02 30 Aug, 2013 3.30.830.10 Assigned
3e4aA03 30 Aug, 2013 3.30.830.10 Assigned
3e4aA04 30 Aug, 2013 3.30.830.10 Assigned
3e4aB01 30 Aug, 2013 3.30.830.10 Assigned
3e4aB02 30 Aug, 2013 3.30.830.10 Assigned
3e4aB03 30 Aug, 2013 3.30.830.10 Assigned
3e4aB04 30 Aug, 2013 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme