PDB 3cda

PDB Information

PDB3CDA
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.070
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cdaA01 26 Jul, 2008 1.10.3270.10 Assigned
3cdaA02 26 Jul, 2008 3.90.770.10 Assigned
3cdaA03 26 Jul, 2008 3.30.70.420 Assigned
3cdaB01 26 Jul, 2008 1.10.3270.10 Assigned
3cdaB02 26 Jul, 2008 3.90.770.10 Assigned
3cdaB03 26 Jul, 2008 3.30.70.420 Assigned
3cdaC01 26 Jul, 2008 1.10.3270.10 Assigned
3cdaC02 26 Jul, 2008 3.90.770.10 Assigned
3cdaC03 26 Jul, 2008 3.30.70.420 Assigned
3cdaD01 26 Jul, 2008 1.10.3270.10 Assigned
3cdaD02 26 Jul, 2008 3.90.770.10 Assigned
3cdaD03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase