PDB Information

PDB3CD7
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.050
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cd7A01 26 Jul, 2008 1.10.3270.10 Assigned
3cd7A02 26 Jul, 2008 3.90.770.10 Assigned
3cd7A03 26 Jul, 2008 3.30.70.420 Assigned
3cd7B01 26 Jul, 2008 1.10.3270.10 Assigned
3cd7B02 26 Jul, 2008 3.90.770.10 Assigned
3cd7B03 26 Jul, 2008 3.30.70.420 Assigned
3cd7C01 26 Jul, 2008 1.10.3270.10 Assigned
3cd7C02 26 Jul, 2008 3.90.770.10 Assigned
3cd7C03 26 Jul, 2008 3.30.70.420 Assigned
3cd7D01 26 Jul, 2008 1.10.3270.10 Assigned
3cd7D02 26 Jul, 2008 3.90.770.10 Assigned
3cd7D03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase