PDB 2h96

PDB Links
Overview

PDB Information

PDB	2H96
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors. Zhao, H., Serby, M.D., Xin, Z., Szczepankiewicz, B.G., Liu, M., Kosogof, C., Liu, B., Nelson, L.T., Johnson, E.F., Wang, S., Pederson, T., Gum, R.J., Clampit, J.E., Haasch, D.L., Abad-Zapatero, C., Fry, E.H., Rondinone, C., Trevillyan, J.M., Sham, H.L., Liu, G. J.Med.Chem.
Header	Transcription
Released	2006-06-09
Resolution	3.000
CATH Insert Date	28 Jul, 2006

PDB Images (9)

Image of CATH 2h96

2h96

PDB 2h96

Image of CATH 2h96A

2h96A

PDB Chain 2h96A

Image of CATH 2h96B

2h96B

PDB Chain 2h96B

Image of CATH 2h96F

2h96F

PDB Chain 2h96F

Image of CATH 2h96G

2h96G

PDB Chain 2h96G

Image of CATH 2h96A01

2h96A01

CATH Domain 2h96A01

Image of CATH 2h96A02

2h96A02

CATH Domain 2h96A02

Image of CATH 2h96B01

2h96B01

CATH Domain 2h96B01

Image of CATH 2h96B02

2h96B02

CATH Domain 2h96B02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	01 Aug, 2006	Chopped
B	01 Aug, 2006	Chopped
F	01 Aug, 2006	Rejected
G	01 Aug, 2006	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2h96A01	16 Oct, 2006	3.30.200.20	Assigned
2h96A02	16 Oct, 2006	1.10.510.10	Assigned
2h96B01	16 Oct, 2006	3.30.200.20	Assigned
2h96B02	16 Oct, 2006	1.10.510.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P45983	MK08_HUMAN	Homo sapiens	Mitogen-activated protein kinase 8
Q9UQF2	JIP1_HUMAN	Homo sapiens	C-Jun-amino-terminal kinase-interacting protein 1
Q9UQF2	JIP1_HUMAN	Homo sapiens	C-Jun-amino-terminal kinase-interacting protein 1
P45983	MK08_HUMAN	Homo sapiens	Mitogen-activated protein kinase 8