PDB 2aei

PDB Links
Overview

PDB Information

PDB	2AEI
Method	X-RAY DIFFRACTION
Host Organism	Cricetulus griseus
Gene Source	Homo sapiens
Primary Citation	The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex. Kohrt, J.T., Filipski, K.J., Cody, W.L., Cai, C., Dudley, D.A., Van Huis, C.A., Willardsen, J.A., Rapundalo, S.T., Saiya-Cork, K., Leadley, R.J., Narasimhan, L., Zhang, E., Whitlow, M., Adler, M., McLean, K., Chou, Y.L., McKnight, C., Arnaiz, D.O., Shaw, K.J., Light, D.R., Edmunds, J.J. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2005-07-22
Resolution	2.520
CATH Insert Date	03 Aug, 2006

PDB Images (9)

Image of CATH 2aei

2aei

PDB 2aei

Image of CATH 2aeiH

2aeiH

PDB Chain 2aeiH

Image of CATH 2aeiL

2aeiL

PDB Chain 2aeiL

Image of CATH 2aeiT

2aeiT

PDB Chain 2aeiT

Image of CATH 2aeiH01

2aeiH01

CATH Domain 2aeiH01

Image of CATH 2aeiH02

2aeiH02

CATH Domain 2aeiH02

Image of CATH 2aeiL01

2aeiL01

CATH Domain 2aeiL01

Image of CATH 2aeiT01

2aeiT01

CATH Domain 2aeiT01

Image of CATH 2aeiT02

2aeiT02

CATH Domain 2aeiT02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
H	03 Aug, 2006	Chopped
L	03 Aug, 2006	Chopped
T	03 Aug, 2006	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2aeiH01	21 Oct, 2006	2.40.10.10	Assigned
2aeiH02	21 Oct, 2006	2.40.10.10	Assigned
2aeiL01	29 Aug, 2007		Holding pen
2aeiT01	15 Oct, 2006	2.60.40.10	Assigned
2aeiT02	15 Oct, 2006	2.60.40.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P13726	TF_HUMAN	Homo sapiens	Tissue factor
P08709	FA7_HUMAN	Homo sapiens	Coagulation factor VII
P08709	FA7_HUMAN	Homo sapiens	Coagulation factor VII