PDB Information

PDB1RW8
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Sawyer, J.S., Beight, D.W., Britt, K.S., Anderson, B.D., Campbell, R.M., Goodson Jr., T., Herron, D.K., Li, H.Y., McMillen, W.T., Mort, N., Parsons, S., Smith, E.C., Wagner, J.R., Yan, L., Zhang, F., Yingling, J.M.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2003-12-16
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1rw8A01 09 Mar, 2006 3.30.200.20 Assigned
1rw8A02 09 Mar, 2006 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1