PDB Information

PDB1RTL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease
Slater, M.J., Amphlett, E.M., Andrews, D.M., Bamborough, P., Carey, S.J., Johnson, M.R., Jones, P.S., Mills, G., Parry, N.R., Somers, D.O., Stewart, A.J., Skarzynski, T.
Org.Lett.
HeaderViral Protein Complex
Released2003-12-10
Resolution2.750
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Rejected
D 05 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1rtlA01 09 Mar, 2006 2.40.10.120 Assigned
1rtlA02 09 Mar, 2006 2.40.10.10 Assigned
1rtlB01 09 Mar, 2006 2.40.10.120 Assigned
1rtlB02 09 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O39914 O39914_9HEPC Hepacivirus C Non-structural protein 4a/b
O39914 O39914_9HEPC Hepacivirus C Non-structural protein 4a/b
P26664 POLG_HCV1 Hepatitis C virus (isolate 1) Genome polyprotein
P26664 POLG_HCV1 Hepatitis C virus (isolate 1) Genome polyprotein