CATH Domain 4oirF01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.1810

Domain Context

CATH Clusters

Superfamily	1.20.120.1810
Functional Family

Enzyme Information

UniProtKB Entries (1)

RPOA_THET8

Thermus thermophilus HB8

DNA-directed RNA polymerase subunit alpha

PDB Structure

PDB	4OIR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Zhang, Y., Degen, D., Ho, M.X., Sineva, E., Ebright, K.Y., Ebright, Y.W., Mekler, V., Vahedian-Movahed, H., Feng, Y., Yin, R., Tuske, S., Irschik, H., Jansen, R., Maffioli, S., Donadio, S., Arnold, E., Ebright, R.H. Elife