CATH Domain 4l8fA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.880	Class I glutamine amidotransferase (GATase) domain

Domain Context

CATH Clusters

Superfamily	3.40.50.880
Functional Family	Folate gamma-glutamyl hydrolase

Enzyme Information

UniProtKB Entries (1)

Q6NY42_DANRE

Danio rerio

Folate gamma-glutamyl hydrolase

PDB Structure

PDB	4L8F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase Chuankhayan, P., Kao, T.-T., Lin, C.-C., Guan, H.-H., Nakagawa, A., Fu, T.-F., Chen, C.-J. J.Med.Chem.