CATH Domain 3ncgA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.200	Phosphorylase Kinase; domain 1
	3.30.200.20	Phosphorylase Kinase; domain 1

Domain Context

CATH Clusters

Superfamily	Phosphorylase Kinase; domain 1
Functional Family	Calcium-dependent protein kinase 3

Enzyme Information

UniProtKB Entries (1)

A3FQ16_CRYPI

Cryptosporidium parvum Iowa II

Calmodulin-domain protein kinase 1, putative

PDB Structure

PDB	3NCG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. Murphy, R.C., Ojo, K.K., Larson, E.T., Castellanos-Gonzalez, A., Perera, B.G., Keyloun, K.R., Kim, J.E., Bhandari, J.G., Muller, N.R., Verlinde, C.L., White, A.C., Merritt, E.A., Van Voorhis, W.C., Maly, D.J. ACS Med Chem Lett