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1 keywords

CATH Domain 3ffzA02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.1120 Clostridium botulinum neurotoxin B, "coiled-coil" domain
Homologous Superfamily 1.20.1120.10 Clostridium botulinum neurotoxin b, "coiled-coil" domain

Domain Context

CATH Clusters

Superfamily Clostridium botulinum neurotoxin b, "coiled-coil" domain
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt Q00496
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

Q00496
BXE_CLOBO
Clostridium botulinum
Botulinum neurotoxin type E

PDB Structure

PDB 3FFZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation.
Kumaran, D., Eswaramoorthy, S., Furey, W., Navaza, J., Sax, M., Swaminathan, S.
J.Mol.Biol.
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