CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.390 | Enolase-like; domain 1 |
|
3.30.390.30 | FAD/NAD-linked reductase, C-terminal dimerisation domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.390.30 |
| Functional Family | Thioredoxin reductase 1, cytoplasmic |
Enzyme Information
| 1.8.1.9 |
Thioredoxin-disulfide reductase.
based on mapping to UniProt O89049
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.
|
UniProtKB Entries (1)
| O89049 |
TRXR1_RAT
Rattus norvegicus
Thioredoxin reductase 1, cytoplasmic
|
PDB Structure
| PDB | 3EAO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1.
J.Biol.Chem.
|
