CATH Domain 3e9lA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.230	Prp8 RNase H domain, palm region

Domain Context

CATH Clusters

Superfamily	3.30.420.230
Functional Family	Pre-mRNA-processing-splicing factor 8

Enzyme Information

UniProtKB Entries (1)

PRP8_HUMAN

Homo sapiens

Pre-mRNA-processing-splicing factor 8

PDB Structure

PDB	3E9L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and function of an RNase H domain at the heart of the spliceosome. Pena, V., Rozov, A., Fabrizio, P., Luhrmann, R., Wahl, M.C. Embo J.