CATH Domain 2p4uC00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.2300	Response regulator

Domain Context

CATH Clusters

Superfamily	3.40.50.2300
Functional Family	Low molecular weight phosphotyrosine protein

Enzyme Information

3.1.3.2	Acid phosphatase. based on mapping to UniProt Q9D358 A phosphate monoester + H(2)O = an alcohol + phosphate. -!- Wide specificity. -!- Also catalyzes transphosphorylations.
3.1.3.48	Protein-tyrosine-phosphatase. based on mapping to UniProt Q9D358 Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

PPAC_MOUSE

Mus musculus

Low molecular weight phosphotyrosine protein phosphatase

PDB Structure

PDB	2P4U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural genomics of protein phosphatases. Almo, S.C., Bonanno, J.B., Sauder, J.M., Emtage, S., Dilorenzo, T.P., Malashkevich, V., Wasserman, S.R., Swaminathan, S., Eswaramoorthy, S., Agarwal, R., Kumaran, D., Madegowda, M., Ragumani, S., Patskovsky, Y., Alvarado, J., Ramagopal, U.A., Faber-Barata, J., Chance, M.R., Sali, A., Fiser, A., Zhang, Z.Y., Lawrence, D.S., Burley, S.K. J.Struct.Funct.Genom.